June 20, 2013

Nuclea Biotechnologies and SUNY's NanoCollege announce $1M partnership to advance nanotechnology-enabled cancer research

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Collaboration is designed to accelerate diagnosis and treatment for breast, colon, prostate and
other cancers through the development of a high-throughput nanochip for testing and analysis

Albany, NY and Pittsfield, MA – Underscoring the strategic blueprint of Governor Andrew M. Cuomo in fueling New York’s growing reputation as a hub for nanotechnology-enabled innovation, SUNY’s College of Nanoscale Science and Engineering (CNSE) and Pittsfield, Massachusetts-based Nuclea Biotechnologies, Inc. (Nuclea) today announced the launch of a $1 million research partnership to enable the development and commercialization of a high-throughput nanochip to accelerate the diagnosis and treatment of breast, colon, prostate and other cancers.

“Driven by the vision and leadership of Governor Andrew Cuomo, New York is recognized as the leading global hub for nanotechnology education and innovation, including an expanding footprint in critical 21st century fields such as life sciences,” said Dr. Alain E. Kaloyeros, CNSE Senior Vice President and CEO. “This public-private partnership with Nuclea Biotechnologies expands CNSE’s cutting-edge research in the nanobioscience arena, and further illustrates its role in accelerating advanced technologies and attracting high-tech companies to New York.”

“This research agreement is a perfect marriage of biotechnology and nanotechnology,” said Patrick Muraca, President and CEO of Nuclea. “CNSE’s global reputation as the world leader in nanoscale engineering will lend critical expertise in developing the miniature version of our protein chip, which is an important element for us as we work toward commercialization. We’ve assembled a great team and look forward to this collaboration with CNSE.”

“This partnership targets important research that offers great promise for improving the quality of life for those stricken with cancer and other deadly diseases,” said Dr. James Castracane, Professor and Head of CNSE’s Nanobioscience Constellation. “We look forward to working with Nuclea Biotechnologies to develop and commercialize new sensing platforms that will enhance disease diagnosis and treatment, and ultimately, promote health care that is more efficient and cost effective.”

In 2005, Nuclea patented an Antibody Protein Analysis Chip to be used in their fatty acid synthase (FAS) analysis. Currently, Nuclea is able to conduct roughly 300 tests per run using the protein chip. Through this partnership with CNSE, the company expects to triple the number of tests that can be performed during each run.

CNSE will utilize its state-of-the-art nanofabrication capabilities to help Nuclea develop a high-throughput nanochip, which would be used as a sensing platform for the analysis of biomarkers associated with cancer and other diseases. This will not only increase the number of tests per run, but will also result in smaller amounts of the biological sample necessary for testing. Concurrently, CNSE will explore methods to support the miniaturization of the protein chip.

Nuclea and CNSE are also discussing additional opportunities for collaboration, which may include the location of a Nuclea office and personnel at CNSE, as well as joint educational and workforce training programs.

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About CNSE. CNSE is the first college in the world dedicated to education, research, development, and deployment in the emerging disciplines of nanoscience, nanoengineering, nanobioscience, and nanoeconomics. With more than $14 billion in high-tech investments, CNSE represents the world's most advanced university-driven research enterprise, offering students a one-of-a-kind academic experience and providing over 300 corporate partners with access to an unmatched ecosystem for leading-edge R&D and commercialization of nanoelectronics and nanotechnology innovations. CNSE’s footprint spans upstate New York, including its Albany NanoTech Complex, an 800,000-square-foot megaplex with the only fully-integrated, 300mm wafer, computer chip pilot prototyping and demonstration line within 85,000 square feet of Class 1 capable cleanrooms. More than 3,100 scientists, researchers, engineers, students, and faculty work here, from companies including IBM, Intel, GlobalFoundries, SEMATECH, Samsung, TSMC, Toshiba, Applied Materials, Tokyo Electron, ASML, and Lam Research. An expansion now underway, part of which will house the world's first Global 450mm Consortium, will add nearly 500,000 square feet of next-generation infrastructure, an additional 50,000 square feet of Class 1 capable cleanrooms, and more than 1,000 scientists, researchers, and engineers from CNSE and global corporations. In addition, CNSE's Solar Energy Development Center in Halfmoon provides a prototyping and demonstration line for next-generation CIGS thin-film solar cells, supporting its leadership of the U.S. Photovoltaic Manufacturing Consortium (PVMC). CNSE’s Smart System Technology and Commercialization Center of Excellence (STC) in Rochester offers state-of-the-art capabilities for MEMS fabrication and packaging. CNSE also co-founded and manages operations at the Computer Chip Commercialization Center at SUNYIT in Utica and is a co-founder of the Nanotechnology Innovation and Commercialization Excelerator in Syracuse. For information, visit www.cnse.albany.edu.

About Nuclea Biotechnologies, Inc
. Headquartered in Pittsfield, Massachusetts with additional operations in Worcester, Massachusetts, Nuclea has developed and is commercializing unique diagnostic tests for colon, breast, leukemia, lung and prostate cancer. Nuclea also performs research leading to novel molecular oncology companion diagnostics for the pharmaceutical and biotechnology industries. http://www.nucleabio.com.

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Media Contacts:

Steve Janack, CNSE Vice President for Marketing and Communications
(518) 956-7322 | sjanack@albany.edu

Greg D’Agostino, Media Relations, Nuclea Biotechnologies
(617) 388-6477 | greg@libertysquaregroup.com